Description

3-Chloro-5-(Trifluoromethyl)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, combining chlorine and trifluoromethyl substituents, provides exceptional reactivity and physicochemical properties for creating complex molecules. This compound is essential for R&D and production chemists in the agrochemical and pharmaceutical industries, where it is used to develop novel active ingredients with enhanced efficacy and stability.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern pesticides, herbicides, and fungicides, particularly those requiring pyridine-based scaffolds for bioactivity.
• Pharmaceutical Building Block: Used in medicinal chemistry for constructing drug candidates, especially in developing active pharmaceutical ingredients (APIs) targeting central nervous system and anti-infective applications.
• Material Science Research: Employed in the development of advanced materials, including liquid crystals, organic semiconductors, and functional polymers.
• Chemical Synthesis Reagent: Acts as a versatile intermediate in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the chlorotrifluoromethylpyridine moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for the custom synthesis of proprietary compounds and development of novel chemical entities.

Basic Information

Product Name	3-Chloro-5-(Trifluoromethyl)Pyridine
CAS No.	85148-26-1
Molecular Formula	C6H3ClF3N
Molecular Weight	181.54 g/mol
Synonyms	5-(Trifluoromethyl)-3-chloropyridine; 3-Chloro-5-(trifluoromethyl)pyridine; 3-Chloro-α,α,α-trifluoro-5-pyridinemethanol (precursor-related); Pyridine, 3-chloro-5-(trifluoromethyl)-; 3-Chloro-5-trifluoromethylpyridine; 85148-26-1; 3-Chloro-5-(trifluoromethyl)pyridine (principal name)
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC for residual solvents, to ensure it meets exacting standards for fine chemical intermediates. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.