Description

4-Azidobenzoyltrimethionine is a specialized biochemical building block featuring a photoreactive azido group and a methionine-derived moiety. This compound matters for researchers and manufacturers requiring precise, photo-inducible crosslinking or labeling in peptide and protein chemistry. It is primarily needed by the pharmaceutical, biotechnology, and advanced materials sectors for applications in drug discovery, proteomics, and the development of smart biomaterials.

Application

• Photoaffinity Labeling Probe: Used in biochemical research to study protein-ligand interactions and binding sites through UV-induced covalent crosslinking.
• Peptide & Protein Modification: Serves as a key reagent for the site-specific incorporation of functional handles or tags into synthetic peptides and engineered proteins.
• Bioconjugation & Click Chemistry: The azide group enables efficient conjugation via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC) reactions.
• Proteomics Research: Employed in activity-based protein profiling (ABPP) and other mass spectrometry-based strategies to identify and characterize enzyme families.
• Material Science: Facilitates the surface functionalization of polymers and nanoparticles for creating bioactive interfaces and targeted delivery systems.
• Diagnostic Reagent Development: Used in the synthesis of components for immunoassays, biosensors, and molecular imaging agents.

Basic Information

Product Name	4-Azidobenzoyltrimethionine
CAS No.	85119-89-7
Molecular Formula	C15H19N5O3S
Molecular Weight	349.41 g/mol
Synonyms	N-(4-Azidobenzoyl)-L-methionine; L-Methionine, N-[(4-azidophenyl)carbonyl]-; 4-Azidobenzoic Acid Methionine Amide; Azidobenzoyl Methionine; ABT-Met; Photo-Methionine Derivative; N-4-Azidobenzoylmethionine
EINECS	Contact for details

Quality Control

Our 4-Azidobenzoyltrimethionine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. The material is light-sensitive and easily oxidized. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.