Description

Gaboxadol Hydrochloride is a high-purity, pharmaceutically relevant compound primarily used in research and development. This compound is significant for its role as a selective extrasynaptic GABAA receptor agonist, making it a valuable tool for neurological and pharmacological studies. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on central nervous system (CNS) drug discovery and neurochemical research.

Application

• Pharmaceutical R&D: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel neurological therapeutics.
• Neuroscience Research: Used as a selective pharmacological tool to study the function of extrasynaptic GABAA receptors and their role in conditions like insomnia, anxiety, and epilepsy.
• Biochemical Assays: Employed in in vitro and in vivo studies to investigate GABAergic neurotransmission and receptor subtype specificity.
• Preclinical Studies: Serves as a critical compound in animal model research for evaluating sedative-hypnotic and anxiolytic effects.
• Chemical Synthesis: Acts as a building block or precursor in the synthesis of more complex molecules targeting the GABA receptor system.
• Analytical Standard: Used in quality control laboratories as a high-purity standard for method development and validation in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	Gaboxadol Hydrochloride
CAS No.	85118-33-8
Molecular Formula	C6H9N3O2·HCl
Molecular Weight	191.61 g/mol (Free base: 155.15)
Synonyms	4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol Hydrochloride; THIP Hydrochloride; Gaboxadol HCl; 3-Hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine Hydrochloride; AATC Hydrochloride
EINECS	Contact for details

Quality Control

Our Gaboxadol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent control of residual solvents and impurities to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.