Description

3-Nitrophenylboronic Acid-1,3-Propanediol Ester is a specialized organoboron compound, serving as a versatile protected boronic acid derivative. This intermediate is critical for enabling controlled Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and advanced material synthesis. It is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical sectors who require high-purity building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key protected boronic acid reagent for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the incorporation of biphenyl or other aryl structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers, where precise aryl-aryl coupling is necessary.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for biological target identification and study.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses serving the life sciences and fine chemical industries.

Basic Information

Product Name	3-Nitrophenylboronic Acid-1,3-Propanediol Ester
CAS No.	85107-44-4
Molecular Formula	C9H10BNO5
Molecular Weight	223.00 g/mol
Synonyms	3-Nitrophenylboronic Acid 1,3-Propanediol Ester; 1,3-Propanediol, 2-(3-nitrophenyl)-1,3,2-dioxaborinane; 2-(3-Nitrophenyl)-1,3,2-dioxaborinane; 3-Nitrophenyl-1,3,2-dioxaborinane; 3-Nitrobenzeneboronic Acid 1,3-Propanediol Cyclic Ester; (3-Nitrophenyl)boronic Acid Propylene Glycol Ester; m-Nitrophenylboronic Acid Cyclic Propylene Ester
EINECS	Contact for details

Quality Control

Our 3-Nitrophenylboronic Acid-1,3-Propanediol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.