Description

Methyl 4-(Bromomethyl)-2-Fluorobenzoate is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its dual functional groups, which enable versatile reactivity for constructing complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to create advanced fluorinated pesticides and herbicides, leveraging the fluorine atom's ability to enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated aromatic cores in electronic and optoelectronic materials.
• Cross-Coupling Reactions: The bromomethyl group is an effective handle for palladium-catalyzed cross-coupling (e.g., Suzuki, Sonogashira) to introduce complex side chains.
• Functional Group Transformation: The ester and benzyl bromide moieties allow for sequential modifications, such as hydrolysis, reduction, or nucleophilic substitution.
• Chemical Biology & Proteomics: Can be utilized to create affinity probes or labeling reagents for studying biological systems.

Basic Information

Product Name	Methyl 4-(Bromomethyl)-2-Fluorobenzoate
CAS No.	85070-57-1
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-Fluoro-4-(bromomethyl)benzoic acid methyl ester; Methyl 2-fluoro-4-(bromomethyl)benzoate; 4-(Bromomethyl)-2-fluorobenzoic acid methyl ester; Benzoic acid, 4-(bromomethyl)-2-fluoro-, methyl ester; Methyl 4-bromomethyl-2-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 4-(Bromomethyl)-2-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.