Description

2,3,6-Trifluoro-4-(Trifluoromethyl)Pyridine is a highly fluorinated pyridine derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring multiple fluorine atoms and a trifluoromethyl group, imparts significant lipophilicity, metabolic stability, and electron-withdrawing properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve bioavailability and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials to modify surface properties and dielectric constants.
• Chemical Biology Probe: Utilized as a building block for fluorinated analogs of biomolecules to study metabolic pathways and protein-ligand interactions.

Basic Information

Product Name	2,3,6-Trifluoro-4-(Trifluoromethyl)Pyridine
CAS No.	84940-46-5
Molecular Formula	C6HF6N
Molecular Weight	201.07 g/mol
Synonyms	4-(Trifluoromethyl)-2,3,6-trifluoropyridine; 2,3,6-Trifluoro-4-trifluoromethylpyridine; Pyridine, 2,3,6-trifluoro-4-(trifluoromethyl)-; 2,3,6-Trifluoro-4-(trifluoromethyl)pyridine; 84940-46-5; 4-(Trifluoromethyl)-2,3,6-trifluoropyridine
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluoro-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride content, ensure containers are properly sealed and handled with appropriate precautions to avoid moisture ingress or contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.