Description

(αr,α'S)-6,6'-Dihydroxy-α,α'-Diisocyano[1,1'-Biphenyl]-3,3'-Dipropionamide is a sophisticated chiral biphenyl derivative featuring diisocyano and dihydroxy functional groups, making it a valuable building block for advanced synthesis. This compound is critical for research and development in asymmetric catalysis and the creation of novel ligand frameworks. It is primarily sought by pharmaceutical R&D teams and specialty chemical manufacturers focused on developing new therapeutic agents and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly those requiring specific stereochemistry.
• Asymmetric Catalyst Ligand: Used in the development of novel metal-organic frameworks (MOFs) and catalysts for enantioselective reactions.
• Advanced Material Research: Employed in the creation of functional polymers and organic electronic materials due to its rigid biphenyl core and reactive isocyano groups.
• Chemical Biology Probes: Acts as a scaffold for designing molecular probes and sensors that target specific biological pathways.
• Academic & Industrial R&D: A vital tool for research institutions and corporate R&D departments exploring new synthetic methodologies.

Basic Information

Product Name	(αr,α'S)-6,6'-Dihydroxy-α,α'-Diisocyano[1,1'-Biphenyl]-3,3'-Dipropionamide
CAS No.	84885-57-4
Molecular Formula	C22H18N4O4
Molecular Weight	402.41 g/mol
Synonyms	6,6'-Dihydroxy-α,α'-diisocyano-1,1'-biphenyl-3,3'-dipropionamide; (R,S)-6,6'-Dihydroxy-α,α'-diisocyano[1,1'-biphenyl]-3,3'-dipropionamide; Biphenyl-3,3'-dipropionamide, 6,6'-dihydroxy-α,α'-diisocyano-; AT-514; NSC 339586; Chiral Biphenyl Diisocyanide; Asymmetric Biphenyl Ligand Precursor
EINECS	Contact for details

Quality Control

Our (αr,α'S)-6,6'-Dihydroxy-α,α'-Diisocyano[1,1'-Biphenyl]-3,3'-Dipropionamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.