Description

3-Pyridinecarbonyl Chloride, 1,2-Dihydro-1-Methyl-2-Oxo- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its reactive carbonyl chloride group makes it an essential reagent for introducing the 1,2-dihydro-1-methyl-2-oxo-3-pyridinecarbonyl moiety into target molecules, enabling the construction of complex pharmacophores. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its heterocyclic structure contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of functionalized polymers and organic electronic materials with specific pyridine-based side chains.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom chemical synthesis houses serving the life sciences sector.
• Academic and R&D Laboratories: Utilized in fundamental research exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 1,2-Dihydro-1-Methyl-2-Oxo- (9Ci)
CAS No.	84854-00-2
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	1-Methyl-2-oxo-1,2-dihydropyridine-3-carbonyl chloride; 1-Methyl-2-oxo-1,2-dihydro-3-pyridinecarbonyl chloride; 3-(Chlorocarbonyl)-1-methyl-2(1H)-pyridinone; 1-Methyl-2-oxo-1,2-dihydro-pyridine-3-carbonyl chloride; N-Methyl-2-oxo-1,2-dihydronicotinoyl chloride; 1-Methyl-2-oxo-1,2-dihydronicotinoyl chloride; 3-Carbamoyl-1-methyl-2-pyridone acid chloride (related); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 1,2-Dihydro-1-Methyl-2-Oxo- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.