Description

tert-Butyl 4-(2-Ethoxy-2-Oxoethyl)-5,6-Dihydropyridine-1(2H)-Carboxylate is a high-purity, protected dihydropyridine derivative serving as a critical advanced intermediate in complex organic syntheses. Its value lies in providing a versatile scaffold for constructing nitrogen-containing heterocycles, which are foundational to numerous active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to streamline multi-step synthesis routes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in classes like calcium channel blockers, neurological agents, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its dihydropyridine core.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, dyes, and functional materials requiring complex nitrogen heterocycles.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for contract research organizations (CROs) developing custom synthesis pathways.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of high-value target molecules.

Basic Information

Product Name	tert-Butyl 4-(2-Ethoxy-2-Oxoethyl)-5,6-Dihydropyridine-1(2H)-Carboxylate
CAS No.	84839-56-5
Molecular Formula	C14H23NO4
Molecular Weight	269.34 g/mol
Synonyms	1-Boc-4-(2-ethoxy-2-oxoethyl)-1,2,3,6-tetrahydropyridine; tert-Butyl 4-(2-ethoxy-2-oxoethyl)-1,2,3,6-tetrahydropyridine-1-carboxylate; 1,2,3,6-Tetrahydro-1-[(1,1-dimethylethoxy)carbonyl]-4-pyridineacetic acid ethyl ester; 4-(2-Ethoxy-2-oxoethyl)-1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine; Ethyl 2-(1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl)acetate; Boc-4-(2-Ethoxy-2-oxoethyl)-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Ethoxy-2-Oxoethyl)-5,6-Dihydropyridine-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.