Description

2,6-Dimethyl-3,5-Dimethoxycarbonyl-4-(p-Difluoromethoxyphenyl)-1,4-Dihydropyridine is a high-purity, synthetically valuable dihydropyridine derivative. This compound serves as a critical advanced intermediate in the research and development of novel active pharmaceutical ingredients (APIs), particularly within the cardiovascular and neurological therapeutic areas. It is essential for pharmaceutical R&D laboratories, fine chemical synthesis units, and academic institutions engaged in medicinal chemistry and process development.

Application

• Key synthetic intermediate for the development of novel calcium channel blockers and other cardiovascular drugs.
• Building block in medicinal chemistry research for creating libraries of dihydropyridine-based compounds.
• Precursor in the synthesis of complex molecules for pharmacological studies targeting neurological disorders.
• Used in process chemistry for route scouting and optimization of API manufacturing processes.
• Reference standard in analytical method development and quality control for related pharmaceutical products.

Basic Information

Product Name	2,6-Dimethyl-3,5-Dimethoxycarbonyl-4-(p-Difluoromethoxyphenyl)-1,4-Dihydropyridine
CAS No.	84761-71-7
Molecular Formula	C19H21F2NO5
Molecular Weight	381.37 g/mol
Synonyms	4-(4-(Difluoromethoxy)phenyl)-2,6-dimethyl-3,5-bis(methoxycarbonyl)-1,4-dihydropyridine; 3,5-Dimethyl 4-[4-(difluoromethoxy)phenyl]-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate; 1,4-DHP Derivative; Difluoromethoxyphenyl DHP; Dihydropyridine Intermediate CAS 84761-71-7
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-3,5-Dimethoxycarbonyl-4-(p-Difluoromethoxyphenyl)-1,4-Dihydropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.