Description

5-Bromo-3-cyano-2-hydroxy-6-methylpyridine is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern, featuring bromo, cyano, and hydroxy functional groups, makes it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic projects requiring high-fidelity intermediates.

Basic Information

Product Name	5-Bromo-3-cyano-2-hydroxy-6-methylpyridine
CAS No.	84725-13-3
Molecular Formula	C7H5BrN2O
Molecular Weight	213.04 g/mol
Synonyms	5-Bromo-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; 2-Hydroxy-5-bromo-6-methylnicotinonitrile; 3-Cyano-5-bromo-2-hydroxy-6-methylpyridine; 5-Bromo-2-hydroxy-6-methyl-3-pyridinecarbonitrile; 84725-13-3; 5-Bromo-3-cyano-2-hydroxy-6-methyl-pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-cyano-2-hydroxy-6-methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.