Description

2,2,6,6-Tetramethylpiperidin-4-Yl Isocyanate is a specialized organic building block featuring a sterically hindered piperidine core with a reactive isocyanate group. This compound matters for its role as a key intermediate in the synthesis of high-performance materials and advanced pharmaceutical agents, where its unique structure imparts stability and specific reactivity. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Synthesis of active pharmaceutical ingredients (APIs), particularly those requiring hindered amine motifs for stability or specific biological activity.
• Polymer Modification: Key monomer for producing polyurethanes and polyurea coatings with enhanced light stability and mechanical properties, often used in high-performance automotive or industrial finishes.
• Agrochemical Synthesis: Building block for advanced crop protection agents and herbicides, leveraging the steric bulk of the tetramethylpiperidine group.
• Ligand and Catalyst Development: Precursor for creating novel nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Surface Functionalization: Grafting agent for modifying material surfaces (e.g., silica, polymers) to introduce reactive isocyanate groups for further conjugation.
• Crosslinking Agent: Used in the formulation of specialty adhesives, sealants, and elastomers requiring controlled reactivity and weatherability.

Basic Information

Product Name	2,2,6,6-Tetramethylpiperidin-4-Yl Isocyanate
CAS No.	84712-82-3
Molecular Formula	C10H18N2O
Molecular Weight	182.26 g/mol
Synonyms	4-Isocyanato-2,2,6,6-tetramethylpiperidine; 2,2,6,6-Tetramethyl-4-piperidyl isocyanate; 4-TMPI; Tempo-4-isocyanate; 2,2,6,6-Tetramethylpiperidin-4-yl isocyanate; 4-Isocyanato-TEMPO; 2,2,6,6-Tetramethyl-4-isocyanatopiperidine
EINECS	Contact for details

Quality Control

Our 2,2,6,6-Tetramethylpiperidin-4-Yl Isocyanate undergoes rigorous quality testing to ensure compliance with industry standards. Production follows strict protocols to guarantee batch-to-batch consistency, purity, and stability. Certificates of Analysis (COA) detailing specific parameters are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.