Description

β-Chlorophenethyl Chloroformate is a specialized organic reagent belonging to the chloroformate ester class. This compound is a valuable building block in synthetic organic chemistry, primarily used for the introduction of the β-chlorophenethyloxycarbonyl (CPOC) protecting group. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require high-purity intermediates for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing protecting groups in multi-step synthesis of complex drug molecules and APIs.
• Peptide Chemistry: Used as a carboxyl-protecting agent for amino acids during solid-phase and solution-phase peptide synthesis.
• Fine Chemical Production: Serves as a versatile building block for creating custom-designed specialty chemicals and advanced materials.
• Agrochemical Research: Employed in the development and synthesis of novel pesticide and herbicide candidates.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the production of specialty polymers with tailored properties.
• Academic & R&D Laboratories: Critical tool for methodological development and exploratory synthesis in organic chemistry research.

Basic Information

Product Name	β-Chlorophenethyl Chloroformate
CAS No.	84697-16-5
Molecular Formula	C9H8Cl2O2
Molecular Weight	219.07 g/mol
Synonyms	2-(2-Chlorophenyl)ethyl chloroformate; (2-Chlorophenethyl) chloroformate; β-Chlorophenethyl chloroformate; CPOC-Cl; 2-Chloro-1-phenylethyl chloroformate; Chloroformic acid 2-(2-chlorophenyl)ethyl ester; 84697-16-5; 2-(2-Chlorophenyl)ethyl carbonochloridate
EINECS	Contact for details

Quality Control

Our β-Chlorophenethyl Chloroformate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.