Description

Cyclobutanecarboxylic Acid, 2-(Cyanomethyl)-, Methyl Ester, trans- (9Ci) is a specialized, high-purity chemical intermediate featuring a unique cyclobutane ring functionalized with both a nitrile and an ester group. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in the synthesis of complex carbocyclic and heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclobutane core can impart specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functional group transformation reactions.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 2-(Cyanomethyl)-, Methyl Ester, trans- (9Ci)
CAS No.	84673-48-3
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	trans-Methyl 2-(cyanomethyl)cyclobutanecarboxylate; Methyl trans-2-(Cyanomethyl)cyclobutanecarboxylate; trans-2-(Cyanomethyl)cyclobutanecarboxylic Acid Methyl Ester; (1r,2r)-2-(Cyanomethyl)cyclobutanecarboxylic Acid Methyl Ester; (1R,2R)-Methyl 2-(cyanomethyl)cyclobutanecarboxylate; Cyclobutanecarboxylic acid, 2-(cyanomethyl)-, methyl ester, trans-; (trans)-Methyl 2-(cyanomethyl)cyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 2-(Cyanomethyl)-, Methyl Ester, trans- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.