Description

Benzamide, n-((5-(5-Chloro-2-Thienyl)-2,3-Dihydro-1-Methyl-1H-1,4-Benz Odiazepin-2-Yl)Methyl)-4-Cyano-, Monohydrochloride is a high-purity, complex organic compound belonging to the benzodiazepine class, specifically formulated as a monohydrochloride salt for enhanced stability and handling. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by R&D chemists, process development scientists, and manufacturers in the pharmaceutical and fine chemical industries seeking a reliable, high-quality building block for complex molecular synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used in the synthesis of compounds for studying and targeting specific receptors within the central nervous system.
• Medicinal Chemistry: Serves as a critical scaffold for structure-activity relationship (SAR) studies to optimize pharmacological properties.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential drug candidates.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Fine Chemical Synthesis: Used as a specialized building block for constructing complex molecular architectures in advanced organic synthesis.

Basic Information

Product Name	Benzamide, n-((5-(5-Chloro-2-Thienyl)-2,3-Dihydro-1-Methyl-1H-1,4-Benz Odiazepin-2-Yl)Methyl)-4-Cyano-, Monohydrochloride
CAS No.	84671-58-9
Molecular Formula	C23H20ClN4OS • HCl
Molecular Weight	473.81 g/mol (Free base: 437.35 g/mol)
Synonyms	4-Cyano-N-[[5-(5-chloro-2-thienyl)-2,3-dihydro-1-methyl-1H-1,4-benzodiazepin-2-yl]methyl]benzamide monohydrochloride; 1-Methyl-2-[[(4-cyanobenzoyl)amino]methyl]-5-(5-chloro-2-thienyl)-2,3-dihydro-1H-1,4-benzodiazepine hydrochloride; A benzodiazepine derivative hydrochloride salt; 84671-58-9 (CAS); 5-(5-Chlorothiophen-2-yl)-1-methyl-2-[(4-cyanobenzamido)methyl]-2,3-dihydro-1H-benzo[e][1,4]diazepine hydrochloride
EINECS	Contact for details

Quality Control

Our Benzamide, n-((5-(5-Chloro-2-Thienyl)-2,3-Dihydro-1-Methyl-1H-1,4-Benz Odiazepin-2-Yl)Methyl)-4-Cyano-, Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, identification by spectroscopic methods (IR, NMR), and tests for specific impurities and residual solvents. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay (on dried basis)	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.