Description

Methyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside is a key protected thioglycoside derivative of L-fucose, serving as a versatile and critical building block in synthetic carbohydrate chemistry. Its primary value lies in its role as a glycosyl donor for the stereoselective construction of complex oligosaccharides and glycoconjugates, enabling precise control over glycosidic linkage formation. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, particularly for the development of carbohydrate-based drugs, vaccines, and molecular probes.

Application

• Glycoscience Research: A fundamental reagent for the chemical and enzymatic synthesis of fucose-containing oligosaccharides and glycans.
• Pharmaceutical Development: Used as a key intermediate in the synthesis of novel glycomimetics, glycoprotein drugs, and carbohydrate-based vaccine candidates.
• Diagnostic Reagent Synthesis: Employed in creating labeled glycans and probes for studying carbohydrate-protein interactions, such as lectin binding assays.
• Bioconjugation: Acts as a starting material for preparing neoglycoconjugates and glycoclusters for targeted drug delivery and imaging applications.
• Enzyme Substrate Studies: Serves as a substrate or inhibitor in the study of fucosyltransferases and other glycosyl-processing enzymes.
• Chemical Biology Tool: Utilized for metabolic oligosaccharide engineering and cell surface labeling strategies.

Basic Information

Product Name	Methyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside
CAS No.	84635-54-1
Molecular Formula	C15H22O8S
Molecular Weight	362.40 g/mol
Synonyms	Methyl 1-Thio-β-L-fucopyranoside 2,3,4-Triacetate; 1-Thio-β-L-fucopyranoside, Methyl, 2,3,4-Triacetate; Methyl 2,3,4-Tri-O-acetyl-1-thio-β-L-fucopyranoside; Methyl 1-Thio-β-L-fucoside Triacetate; β-L-Fucopyranoside, Methyl 1-Thio-, 2,3,4-Triacetate; Thiomethyl 2,3,4-Tri-O-acetyl-β-L-fucopyranoside; Protected L-Fucose Thioglycoside Donor
EINECS	Contact for details

Quality Control

Our Methyl 2,3,4-Tri-o-Acetyl-1-Thio-β-L-Fucopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.