Description

p-(T-Butyldimethylsiloxy)Styrene is a high-value, protected styrene derivative featuring a tert-butyldimethylsilyl (TBDMS) ether group on the para position. This compound is a crucial advanced intermediate for synthesizing complex organic molecules, offering exceptional versatility in fine chemical and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex structures.
• Polymer & Materials Science: Monomer for creating specialty polymers with tailored properties, such as functionalized polystyrene derivatives or siloxane-containing hybrid materials.
• Agrochemical Synthesis: Intermediate in the development of advanced crop protection agents and herbicides requiring specific aromatic substitution patterns.
• Liquid Crystal & OLED Materials: Precursor for synthesizing functional organic molecules used in electronic displays and optoelectronic devices.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) due to the reactive vinyl group adjacent to the protected phenol.
• Protecting Group Strategy: The TBDMS-protected phenol serves as a stable handle for multi-step synthetic sequences, which can be deprotected under mild conditions when needed.

Basic Information

Product Name	p-(T-Butyldimethylsiloxy)Styrene
CAS No.	84494-81-5
Molecular Formula	C₁₄H₂₂OSi
Molecular Weight	234.41 g/mol
Synonyms	4-[(tert-Butyldimethylsilyl)oxy]styrene; 4-Vinylphenol tert-butyldimethylsilyl ether; 4-(TBDMS-Oxy)styrene; p-Styryloxy-tert-butyldimethylsilane; 4-Ethenylphenol 1,1-dimethylethyl)dimethylsilyl ether; 4-(tert-Butyl(dimethyl)silyl)oxy)styrene; TBDMS-protected 4-vinylphenol
EINECS	Contact for details

Quality Control

Our p-(T-Butyldimethylsiloxy)Styrene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.