Description

(E)-3-(2,4-Dimethoxyphenyl)-1-(2-Hydroxy-4-Methoxyphenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct molecular structure featuring methoxy and hydroxy substituents. This compound serves as a critical intermediate and building block in advanced organic synthesis, valued for its specific photophysical and chemical reactivity. It is primarily required by pharmaceutical R&D, fine chemical synthesis, and advanced material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting inflammatory or metabolic pathways.
• Organic Light-Emitting Diode (OLED) Research: Used as a core structure for developing emissive or charge-transport materials due to its conjugated system.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex natural product analogs and specialty chemicals.
• UV-Absorbing Agent Development: Explored for use in formulating advanced sunscreens or protective coatings owing to its chromophore.
• Biochemical Probe: Utilized in research to study enzyme inhibition or specific protein-ligand interactions.
• Material Science: Investigated as a monomer or cross-linking agent for polymers with specific optical properties.

Basic Information

Product Name	(E)-3-(2,4-Dimethoxyphenyl)-1-(2-Hydroxy-4-Methoxyphenyl)Prop-2-En-1-One
CAS No.	84426-23-3
Molecular Formula	C18H18O5
Molecular Weight	314.33 g/mol
Synonyms	2'-Hydroxy-2,4,4'-Trimethoxychalcone; (E)-1-(2-Hydroxy-4-methoxyphenyl)-3-(2,4-dimethoxyphenyl)-2-propen-1-one; 2-Propen-1-one, 1-(2-hydroxy-4-methoxyphenyl)-3-(2,4-dimethoxyphenyl)-, (E)-; NSC 407303; 2,4,2'-Trimethoxychalcone-4'-ol; Chalcone derivative 84426-23-3; Light-sensitive chalcone intermediate
EINECS	Contact for details

Quality Control

Our (E)-3-(2,4-Dimethoxyphenyl)-1-(2-Hydroxy-4-Methoxyphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in GMP-aligned applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.