Description

2-(Dimethylamino)Ethyl 4-Azidobenzoate is a specialized organic compound featuring both an azido group and a benzoate ester linked to a tertiary amine moiety. This unique bifunctional structure makes it a valuable intermediate for photoaffinity labeling and click chemistry applications in advanced research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors for synthesizing probes, polymers, and functionalized surfaces.

Application

• Photoaffinity Labeling Probes: A key reagent for synthesizing covalent probes to study protein-ligand interactions and biological target identification.
• Click Chemistry Reagent: Serves as an azide-containing building block for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create complex molecular architectures.
• Polymer & Materials Functionalization: Used to introduce photo-reactive and clickable sites into polymers, hydrogels, and surface coatings for advanced material properties.
• Bioconjugation Linker: Enables the covalent attachment of dyes, drugs, or other molecules to biomolecules like antibodies or peptides for diagnostic and therapeutic applications.
• Chemical Biology Research: Employed in the development of activity-based probes and for mapping enzyme active sites.
• Cross-linking Agent: Facilitates the formation of cross-linked networks in specialty polymers upon UV light activation.

Basic Information

Product Name	2-(Dimethylamino)Ethyl 4-Azidobenzoate
CAS No.	84389-35-5
Molecular Formula	C11H14N4O2
Molecular Weight	234.26 g/mol
Synonyms	4-Azidobenzoic Acid 2-(Dimethylamino)ethyl Ester; 2-(Dimethylamino)ethyl p-Azidobenzoate; DMABA; N,N-Dimethylaminoethyl 4-Azidobenzoate; p-Azidobenzoic Acid Dimethylaminoethyl Ester; 4-Azido-N,N-dimethylaminobenzoate; Benzoic acid, 4-azido-, 2-(dimethylamino)ethyl ester; Photoactive DMAP ester derivative
EINECS	Contact for details

Quality Control

Our 2-(Dimethylamino)Ethyl 4-Azidobenzoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance for sensitive research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the material should be handled under an inert atmosphere when appropriate and protected from moisture to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.