Description

4,7,8,9-Tetra-o-Acetyl-n-Acetylneuraminic Acid Methyl Ester is a key protected derivative of N-acetylneuraminic acid, a fundamental sialic acid. This compound is essential as a critical synthetic intermediate in the production of complex oligosaccharides, glycoconjugates, and sialylated bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for advanced glycosylation reactions and the development of novel therapeutics and diagnostic tools.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of sialic acid-containing drugs, including antiviral agents, anti-inflammatory medications, and cancer therapeutics.
• Glycobiology Research: Used in enzymatic and chemical synthesis to study sialic acid biology, cell signaling, and pathogen-host interactions.
• Oligosaccharide Synthesis: Serves as a protected donor molecule for constructing complex carbohydrate chains (glycans) for biochemical probes and standards.
• Glycoconjugate Production: Enables the creation of sialylated glycoproteins and glycolipids for vaccine development and targeted drug delivery systems.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of high-value chiral compounds and specialty chemicals.
• Diagnostic Reagent Development: Used to produce components for diagnostic assays that detect sialic acid-related biomarkers.

Basic Information

Product Name	4,7,8,9-Tetra-o-Acetyl-n-Acetylneuraminic Acid Methyl Ester
CAS No.	84380-10-9
Molecular Formula	C22H33NO15
Molecular Weight	551.50 g/mol
Synonyms	Methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonate; Methyl 4,7,8,9-tetra-O-acetyl-N-acetylneuraminate; N-Acetylneuraminic Acid Methyl Ester Tetraacetate; Sialic Acid Methyl Ester Tetraacetate; Neu5Ac Methyl Ester Tetraacetate; 4,7,8,9-Tetra-O-acetyl-N-acetylneuraminic Acid Methyl Ester; 84380-10-9; Methyl (5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosid)onate
EINECS	Contact for details

Quality Control

Our 4,7,8,9-Tetra-o-Acetyl-n-Acetylneuraminic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.