Description

Piperidine-1,4-Dicarboxylic Acid 4-tert-Butyl Ester 1-(2,5-Dioxo-Pyrrolidin-1-Yl) Ester is a high-purity, specialty chemical building block designed for advanced organic synthesis. This compound is valued for its dual functionality, incorporating both a protected carboxylic acid group and an activated ester moiety, which facilitates efficient and selective coupling reactions. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing piperidine scaffolds.
• Peptide Mimetics & Conjugation: Used for the controlled introduction of piperidine-4-carboxylic acid derivatives into peptides or proteins via its activated NHS ester group.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Material Science & Polymer Chemistry: Employed in the creation of functional monomers and cross-linkers for specialty polymers with tailored properties.
• Bioconjugation & Probe Development: Facilitates the labeling of biomolecules (e.g., antibodies, enzymes) with fluorescent or affinity tags for diagnostic applications.
• Chemical Biology Research: Utilized as a tool compound for studying enzyme inhibition or modulating protein-protein interactions.

Basic Information

Product Name	Piperidine-1,4-Dicarboxylic Acid 4-tert-Butyl Ester 1-(2,5-Dioxo-Pyrrolidin-1-Yl) Ester
CAS No.	84358-15-6
Molecular Formula	C16H24N2O6
Molecular Weight	340.38 g/mol
Synonyms	1-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-1-oxo-4-(1,1-dimethylethoxy)-1,4-piperidinedicarboxylate; 4-(tert-Butoxy)-1-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}piperidine-4-carboxylic acid; 1-N-Succinimidyl 4-tert-butoxycarbonyl-4-piperidinecarboxylate; 4-Boc-piperidine-4-carboxylic acid N-hydroxysuccinimide ester; 4-(Boc-amino)-1-piperidinecarboxylic acid N-succinimidyl ester; NHS ester of 4-Boc-aminopiperidine-4-carboxylic acid; 84358-15-6; tert-Butyl 4-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}carbamoyl)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our Piperidine-1,4-Dicarboxylic Acid 4-tert-Butyl Ester 1-(2,5-Dioxo-Pyrrolidin-1-Yl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.