Description

N,N'-Bis(Trifluoroacetyl)-L-Homocystine Dimethyl Ester is a high-purity, fluorinated derivative of the amino acid homocystine, designed for advanced research and synthesis. This compound serves as a critical protected intermediate and building block in the development of novel pharmaceuticals and bioactive peptides. It is primarily utilized by researchers and process chemists in pharmaceutical R&D, agrochemical discovery, and advanced material science for introducing specific fluorinated motifs and disulfide linkages.

Application

• Pharmaceutical Intermediate: A key protected building block for the synthesis of fluorinated peptide analogs and potential drug candidates.
• Bioconjugation Chemistry: Used in the development of linkers and cross-linking agents for antibody-drug conjugates (ADCs) and protein labeling.
• Proteomics Research: Serves as a specialty reagent for studying disulfide bond formation and protein folding mechanisms.
• Agrochemical Synthesis: Employed as an intermediate in creating novel, fluorinated active ingredients with enhanced properties.
• Material Science: Acts as a precursor for specialty polymers and advanced organic frameworks that incorporate fluorinated and sulfur-containing groups.

Basic Information

Product Name	N,N'-Bis(Trifluoroacetyl)-L-Homocystine Dimethyl Ester
CAS No.	84355-09-9
Molecular Formula	C16H18F6N2O6S2
Molecular Weight	512.45 g/mol
Synonyms	L-Homocystine, N,N'-bis(trifluoroacetyl)-, dimethyl ester; Bis(trifluoroacetyl)homocystine dimethyl ester; Dimethyl N,N'-bis(2,2,2-trifluoroacetyl)-L-homocystinate; (2R,2'R)-Dimethyl 2,2'-(disulfanediyl)bis(4-(2,2,2-trifluoroacetamido)butanoate); N,N'-Di(trifluoroacetyl)-L-homocystine dimethyl ester; Trifluoroacetyl-L-homocystine dimethyl ester; TFA-Hcy(OMe)-Hcy(OMe)-TFA
EINECS	Contact for details

Quality Control

Our N,N'-Bis(Trifluoroacetyl)-L-Homocystine Dimethyl Ester is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.