Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (1R-Exo)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant value in advanced organic synthesis. Its rigid, strained bicyclic framework and defined exo stereochemistry make it an essential intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for applications in asymmetric synthesis, catalyst development, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of specialized ligands for transition metal catalysis, enabling highly enantioselective transformations critical for producing single-isomer compounds.
• Agrochemical Synthesis: Serves as a building block for developing advanced, stereospecific pesticides and herbicides where biological activity is highly dependent on molecular geometry.
• Material Science Research: Employed in the development of novel polymers and advanced organic materials with specific structural and optical properties derived from its strained norbornene core.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic synthesis, including Diels-Alder reactions and ring-opening metathesis polymerizations (ROMP).
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, naturally derived odorants and flavor compounds with specific stereochemical profiles.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (1R-Exo)- (9Ci)
CAS No.	84235-37-0
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(1R-exo)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester; Methyl (1R-exo)-bicyclo[2.2.1]hept-5-ene-2-carboxylate; (1R,2S,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester; exo-Methyl 5-norbornene-2-carboxylate (1R); (1R)-exo-2-Methoxycarbonylbicyclo[2.2.1]hept-5-ene; Norborn-5-ene-2-carboxylic acid, methyl ester, (1R-exo)-; Methyl (1R,2S,4R)-5-norbornene-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (1R-Exo)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are subjected to rigorous analytical testing, including chiral purity analysis, to meet the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by GC/HPLC), enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.