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Diethyl 2-(2-(Pyridin-2-Yl)Ethyl)Malonate CAS NO 84199-92-8


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CAS No.:84199-92-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Diethyl 2-(2-(Pyridin-2-Yl)Ethyl)Malonate is a specialized malonate ester derivative featuring a pyridyl-ethyl side chain, serving as a versatile and high-value synthetic intermediate. This compound is crucial for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring the introduction of a functionalized malonate moiety adjacent to a nitrogen-containing heterocycle.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its structure contributes to specific biological activity and selectivity.
  • Fine Chemical Production: Serves as a precursor for synthesizing specialty chemicals, ligands for catalysis, and other high-value organic compounds.
  • Research & Development: Essential tool compound in medicinal chemistry for structure-activity relationship (SAR) studies and novel scaffold exploration.
  • Chemical Synthesis: Employed in Knoevenagel condensations, Michael additions, and other carbon-carbon bond-forming reactions to create complex esters and acids.

Basic Information

Product Name Diethyl 2-(2-(Pyridin-2-Yl)Ethyl)Malonate
CAS No. 84199-92-8
Molecular Formula C₁₄H₁₉NO₄
Molecular Weight 265.31 g/mol
Synonyms Diethyl (2-pyridin-2-ylethyl)malonate; 2-(2-Pyridin-2-ylethyl)malonic Acid Diethyl Ester; Propanedioic acid, 2-[2-(2-pyridinyl)ethyl]-, 1,3-diethyl ester; Diethyl 2-(2-pyridin-2-ylethyl)propanedioate; 2-Pyridineethanemalonic Acid Diethyl Ester; Malonic acid, (2-(2-pyridyl)ethyl)-, diethyl ester
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Quality Control

Our Diethyl 2-(2-(Pyridin-2-Yl)Ethyl)Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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