Description

23,25-Dihydroxy-24-Oxovitamin D3 is a key metabolite and synthetic intermediate in the vitamin D pathway. This compound is crucial for research into calcium homeostasis, bone metabolism, and the development of novel vitamin D analogs for therapeutic applications. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity biochemicals.

Application

• Pharmaceutical Research & Development: A critical reference standard and synthetic precursor for developing novel vitamin D receptor (VDR) modulators and active pharmaceutical ingredients (APIs).
• Biochemical Studies: Used to investigate the metabolic pathways of vitamin D, its role in gene regulation, and its effects on cellular differentiation and proliferation.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Nutraceutical Development: Employed in the research and formulation of advanced nutritional supplements targeting bone health and immune system modulation.
• Endocrinology Research: Essential for studying hormonal regulation, calcium and phosphate balance, and related endocrine disorders.

Basic Information

Product Name	23,25-Dihydroxy-24-Oxovitamin D3
CAS No.	84164-55-6
Molecular Formula	C₂₇H₄₂O₅
Molecular Weight	446.62 g/mol
Synonyms	24-Oxo-23,25-dihydroxyvitamin D3; 23,25-Dihydroxy-24-oxocholecalciferol; 1α,25-Dihydroxy-24-oxovitamin D3 (related isomer); 24-Oxocalcitriol metabolite; Vitamin D3 metabolite 24-oxo-23,25-(OH)₂D₃; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
EINECS	Contact for details

Quality Control

Our 23,25-Dihydroxy-24-Oxovitamin D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label or COA. This product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.