Description

1-Methylspiro[4H-3,1-Benzoxazine-4,4'-Piperidin]-2(1H)-One is a high-purity, complex heterocyclic compound featuring a unique spirocyclic architecture. This structural motif makes it a valuable and versatile advanced pharmaceutical intermediate for research and development. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Organic Synthesis: Serves as a sophisticated precursor for constructing spirocyclic and fused heterocyclic compounds in academic and industrial labs.
• Chemical Reference Standard: Employed as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1-Methylspiro[4H-3,1-Benzoxazine-4,4'-Piperidin]-2(1H)-One
CAS No.	84060-10-6
Molecular Formula	C14H16N2O2
Molecular Weight	244.29 g/mol
Synonyms	1-Methylspiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one; 1-Methyl-1-azaspiro[4.5]decane-2,8-dione benzoxazine derivative; Spiro[4H-3,1-benzoxazine-4,4'-piperidine]-2(1H)-one, 1-methyl-; 84060-10-6; 1-Methylspiro(benzoxazine-4,4'-piperidin)-2-one
EINECS	Contact for details

Quality Control

Our 1-Methylspiro[4H-3,1-Benzoxazine-4,4'-Piperidin]-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.