Description

4'-Isocyanatobenzo-15-Crown-5 is a specialized crown ether derivative featuring a reactive isocyanate functional group, making it a valuable building block for synthesizing advanced host-guest complexes and functional materials. This compound is particularly significant for its ability to selectively bind alkali metal cations, which can be leveraged to create smart polymers, sensors, and separation membranes. It is primarily needed by researchers and manufacturers in the fields of supramolecular chemistry, materials science, and analytical chemistry for developing ion-selective systems and novel polymeric architectures.

Application

• Supramolecular Chemistry Building Block: Used as a key precursor for synthesizing crown ether-based receptors, rotaxanes, and catenanes with tailored ion-binding properties.
• Polymer Modification: The reactive isocyanate group enables covalent attachment to polymers, creating functional materials for ion-selective membranes or coatings.
• Chemical Sensor Development: Incorporated into sensor platforms for the selective detection and quantification of specific alkali metal ions like potassium or sodium.
• Chromatography & Separation Science: Can be immobilized on silica or polymer supports to create stationary phases for the chromatographic separation of ionic species.
• Catalysis: Serves as a ligand or support modifier in catalytic systems where metal ion sequestration is required to influence reaction pathways.
• Academic & Industrial Research: A critical reagent for fundamental studies in host-guest chemistry and the development of new functional materials.

Basic Information

Product Name	4'-Isocyanatobenzo-15-Crown-5
CAS No.	83935-62-0
Molecular Formula	C17H23NO7
Molecular Weight	353.37 g/mol
Synonyms	1-Isocyanato-4',4'',5',5'',6',6''-hexahydro-5,6:11,12-dibenzo-1,4,7,10,13-pentaoxacyclopentadecin-2',3'-ylene; Benzo-15-crown-5 isocyanate; 4'-Isocyanato-benzo-15-crown-5; 15-Crown-5 isocyanate derivative; B15C5-NCO; 1,4,7,10,13-Pentaoxacyclopentadec-2-ylmethyl 4-isocyanatobenzoate (related structure); 4-Isocyanatobenzo[15]crown-5
EINECS	Contact for details

Quality Control

Our 4'-Isocyanatobenzo-15-Crown-5 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research and advanced material synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Isocyanate Content (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.