Description

Benzyl 3-Methyl-4-Phenyl-1-(p-Tolylsulphonyl)Piperidine-4-Carboxylate CAS NO 83898-25-3 is a high-purity, synthetically valuable piperidine derivative featuring a benzyl ester and a tosyl-protected amine. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in sophisticated organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Research: Used in the development of new active ingredients for crop protection and pest management.
• Organic Synthesis Reagent: A versatile scaffold for constructing complex piperidine-based heterocycles and other pharmacophores in medicinal chemistry.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Used in university and institutional labs for fundamental research in synthetic methodology and compound library generation.

Basic Information

Product Name	Benzyl 3-Methyl-4-Phenyl-1-(p-Tolylsulphonyl)Piperidine-4-Carboxylate
CAS No.	83898-25-3
Molecular Formula	C27H29NO4S
Molecular Weight	463.59 g/mol
Synonyms	1-[(4-Methylphenyl)sulfonyl]-4-phenyl-3-methyl-4-piperidinecarboxylic Acid Benzyl Ester; Benzyl 3-Methyl-4-Phenyl-1-Tosylpiperidine-4-Carboxylate; 1-Tosyl-3-methyl-4-phenylpiperidine-4-carboxylic Acid Benzyl Ester; 4-Phenyl-3-methyl-1-tosyl-4-piperidinecarboxylic Acid Benzyl Ester; 83898-25-3; Benzyl 1-Tosyl-3-methyl-4-phenylpiperidine-4-carboxylate; 4-(Benzyloxycarbonyl)-3-methyl-4-phenyl-1-tosylpiperidine
EINECS	Contact for details

Quality Control

Our production of Benzyl 3-Methyl-4-Phenyl-1-(p-Tolylsulphonyl)Piperidine-4-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, and we welcome audits and quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.