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[1R-(1Alpha,2Beta,5Alpha)]-[[2-Isopropyl-5-Methylcyclohexyl]Oxy]Dimethoxymethylsilane CAS NO 83863-60-9


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CAS No.:83863-60-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[1R-(1Alpha,2Beta,5Alpha)]-[[2-Isopropyl-5-Methylcyclohexyl]Oxy]Dimethoxymethylsilane is a high-purity, chiral organosilicon compound designed for advanced chemical synthesis. This specialty silane is valued for its role as a key intermediate and protecting group in the production of complex molecules, particularly in the pharmaceutical and fine chemical sectors. It is essential for researchers and manufacturers requiring precise stereochemical control and functional group manipulation in their synthetic pathways.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) where its chiral center and silane functionality are utilized.
  • Asymmetric Synthesis: Employed as a chiral auxiliary or reagent in stereoselective reactions to produce enantiomerically enriched compounds.
  • Silicon-Based Protecting Groups: Used to protect hydroxyl groups during multi-step organic synthesis, offering stability under specific reaction conditions.
  • Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances.
  • Material Science Research: Investigated for potential applications in modifying surface properties or creating novel silicon-containing polymers.

Basic Information

Product Name [1R-(1Alpha,2Beta,5Alpha)]-[[2-Isopropyl-5-Methylcyclohexyl]Oxy]Dimethoxymethylsilane
CAS No. 83863-60-9
Molecular Formula C14H30O3Si
Molecular Weight 274.48 g/mol
Synonyms (-)-Menthyl Dimethoxymethylsilane; (1R,2S,5R)-(-)-Menthyl Dimethoxymethylsilane; L-Menthyl Dimethoxymethylsilane; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Dimethoxymethylsilane Ether; Dimethoxy(methyl)[(1R,2S,5R)-2-(propan-2-yl)-5-methylcyclohexoxy]silane; Menthyl (dimethoxy)methylsilane; (-)-Menthyl (dimethoxy)methylsilane
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Quality Control

Our production of [1R-(1Alpha,2Beta,5Alpha)]-[[2-Isopropyl-5-Methylcyclohexyl]Oxy]Dimethoxymethylsilane adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, GC, and NMR, to confirm identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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