Description

Ethyl 4-Hydroxy-4-(p-Tolyl)Piperidine-1-Carboxylate is a high-purity, functionalized piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is essential for constructing complex pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and analgesic drug candidates.
• Chemical Synthesis Building Block: Used for constructing complex heterocyclic compounds and fine chemicals due to its reactive hydroxyl and ester functional groups.
• Agrochemical Research: Employed in the synthesis of experimental compounds for crop protection and agrochemical discovery programs.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological studies and process chemistry optimization within laboratory settings.
• Custom Synthesis Projects: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly and scale-up projects.

Basic Information

Item	Detail
Product Name	Ethyl 4-Hydroxy-4-(p-Tolyl)Piperidine-1-Carboxylate
CAS No.	83846-82-6
Molecular Formula	C15H21NO3
Molecular Weight	263.33 g/mol
Synonyms	1-Carbethoxy-4-hydroxy-4-(4-methylphenyl)piperidine; Ethyl 4-hydroxy-4-(4-methylphenyl)-1-piperidinecarboxylate; 4-Hydroxy-4-(p-tolyl)piperidine-1-carboxylic acid ethyl ester; 4-(4-Methylphenyl)-4-hydroxypiperidine-1-carboxylic acid ethyl ester; 1-Piperidinecarboxylic acid, 4-hydroxy-4-(4-methylphenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-4-(p-Tolyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.