Description

(3R,6R,9R)-9-Ethyl-4β-Hydroxy-1,7-Dioxaspiro[5.5]Undecane-3β-Methanol is a high-purity, stereochemically defined spirocyclic compound that serves as a valuable chiral building block and intermediate in advanced organic synthesis. Its complex, rigid structure makes it a critical precursor for the development of novel pharmaceuticals, agrochemicals, and specialty materials where precise three-dimensional architecture is required. This compound is essential for research and development chemists in fine chemical, pharmaceutical, and biotechnology industries seeking to create molecules with specific biological activity or material properties.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and neurological drug candidates.
• Agrochemical Synthesis: Used as a building block for creating novel, stereospecific pesticides, herbicides, and plant growth regulators with enhanced efficacy and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated for incorporation into advanced polymers, liquid crystals, or supramolecular assemblies to impart specific chiral or structural properties.
• Flavor & Fragrance Chemistry: Potential intermediate for the synthesis of complex, naturally-derived odorants and flavoring agents with high stereochemical purity.
• Academic & Industrial R&D: A valuable reference standard and research chemical for studying spirocyclic chemistry, reaction mechanisms, and structure-activity relationships.

Basic Information

Product Name	(3R,6R,9R)-9-Ethyl-4β-Hydroxy-1,7-Dioxaspiro[5.5]Undecane-3β-Methanol
CAS No.	83720-10-9
Molecular Formula	C13H22O4
Molecular Weight	242.31 g/mol
Synonyms	9-Ethyl-4β-hydroxy-1,7-dioxaspiro[5.5]undecane-3β-methanol; (3R,6R,9R)-9-Ethyl-4-hydroxy-1,7-dioxaspiro[5.5]undecane-3-methanol; Spiro[1,3-dioxane-5,2'-1,3-dioxane]-3-methanol, 9-ethyl-4-hydroxy-, (3R,6R,9R)-; 1,7-Dioxaspiro[5.5]undecane-3-methanol, 9-ethyl-4-hydroxy-, (3R,6R,9R)-; Chiral spirocyclic diol derivative
EINECS	Contact for details

Quality Control

Our (3R,6R,9R)-9-Ethyl-4β-Hydroxy-1,7-Dioxaspiro[5.5]Undecane-3β-Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and optical rotation measurement to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.