Description

6-Chloromethyl-Nicotinonitrile is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its reactive chloromethyl and nitrile groups make it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	6-Chloromethyl-Nicotinonitrile
CAS No.	83640-36-2
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	6-(Chloromethyl)nicotinonitrile; 3-Cyano-6-(chloromethyl)pyridine; 6-Chloromethyl-3-cyanopyridine; Nicotinonitrile, 6-(chloromethyl)-; Pyridine, 3-cyano-6-(chloromethyl)-; 2-Chloromethyl-5-cyanopyridine; 5-Cyano-2-(chloromethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Chloromethyl-Nicotinonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.