Description

8-Benzylidene-1,4-Dioxaspiro[4.5]Decane is a specialized organic compound featuring a spirocyclic acetal structure, which serves as a versatile synthetic intermediate and building block in advanced organic synthesis. Its unique molecular architecture, incorporating both a benzylidene group and a protected ketone equivalent, makes it valuable for constructing complex molecules with precise stereochemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring spirocyclic or bridged ring systems.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the spiroacetal moiety can impart specific biological activity.
• Fine Chemical Synthesis: Serves as a chiral building block or protecting group strategy in the multi-step synthesis of fragrances, flavors, and specialty chemicals.
• Material Science: Investigated as a monomer or cross-linking agent for the development of polymers with unique thermal or mechanical properties.
• Academic & R&D: Employed in methodological studies and as a model substrate for developing new catalytic reactions, such as asymmetric hydrogenations or cross-couplings.

Basic Information

Product Name	8-Benzylidene-1,4-Dioxaspiro[4.5]Decane
CAS No.	83631-87-2
Molecular Formula	C₁₇H₂₀O₂
Molecular Weight	256.34 g/mol
Synonyms	8-Benzylidene-1,4-dioxaspiro[4.5]decane; 2-(Phenylmethylene)-1,4-dioxaspiro[4.5]decane; 8-Benzylidene-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decane, 8-(phenylmethylene)-; 8-Benzylidene-1,4-dioxaspiro[4,5]decane; Spiro[1,3-dioxolane-2,1'-cyclohexane], 5-(phenylmethylene)-; 5-(Phenylmethylene)spiro[1,3-dioxolane-2,1'-cyclohexane]
EINECS	Contact for details

Quality Control

Our 8-Benzylidene-1,4-Dioxaspiro[4.5]Decane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurity profiles is provided with every shipment. We support cGMP and ISO compliant production for critical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.