Description

(S)-Dimethyl Pyrrolidine-1,2-Dicarboxylate is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable precursor for the development of active pharmaceutical ingredients (APIs) and complex organic molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel compounds and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various APIs, including potential candidates for neurological and cardiovascular therapies.
• Asymmetric Catalysis Ligand Precursor: Used to synthesize chiral ligands and catalysts for enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating novel, stereochemically defined pesticides and herbicides.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances.
• Academic & Industrial Research: A valuable tool for medicinal chemistry programs and methodology development in organic synthesis.
• Peptidomimetic Scaffold Development: Used in the design and synthesis of conformationally constrained peptide analogs.

Basic Information

Product Name	(S)-Dimethyl Pyrrolidine-1,2-Dicarboxylate
CAS No.	83541-81-5
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	(2S)-1,2-Pyrrolidinedicarboxylic acid dimethyl ester; Dimethyl (S)-(-)-1,2-pyrrolidinedicarboxylate; (S)-(-)-1,2-Pyrrolidinedicarboxylic acid dimethyl ester; L-Proline dimethyl ester; (S)-Proline dimethyl ester; (S)-1,2-Dimethyl pyrrolidine-1,2-dicarboxylate; (S)-Dimethyl 1,2-pyrrolidinedicarboxylate
EINECS	Contact for details

Quality Control

Our (S)-Dimethyl Pyrrolidine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.