Description

(-)-Diisopropyl-L-Malate CAS NO 83541-68-8 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis and pharmaceutical manufacturing. Its defined stereochemistry makes it a valuable reagent for the preparation of enantiomerically pure compounds, particularly in the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for research institutions, contract development and manufacturing organizations (CDMOs), and producers of advanced chiral molecules.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material or resolving agent for the production of enantiomerically pure drugs.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of chiral ligands for metal-catalyzed reactions.
• Fine Chemical and Specialty Chemical Production: Employed in the manufacture of complex organic molecules requiring high stereochemical fidelity.
• Academic and Industrial Research: Serves as a standard or reagent in methodological development for stereoselective transformations.
• Flavor and Fragrance Industry: Potential use in the synthesis of chiral aroma compounds and esters.
• Agrochemical Intermediate: Can be utilized in the synthesis of chiral active ingredients for crop protection.

Basic Information

Product Name	(-)-Diisopropyl-L-Malate
CAS No.	83541-68-8
Molecular Formula	C10H18O5
Molecular Weight	218.25 g/mol
Synonyms	L-(-)-Diisopropyl Malate; Diisopropyl L-Malate; (S)-Diisopropyl 2-Hydroxysuccinate; (-)-Diisopropyl (S)-Malate; Diisopropyl (2S)-2-Hydroxybutanedioate; L-Malic Acid Diisopropyl Ester; (S)-(-)-Malic Acid Diisopropyl Ester
EINECS	Contact for details

Quality Control

Our (-)-Diisopropyl-L-Malate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to meet the stringent requirements of pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.