Description

4(5)-(2-(4-Azido-2-Nitroanilino)Ethyl)Imidazole is a specialized heterocyclic organic compound featuring a unique azido-nitroaniline functional group attached to an imidazole core via an ethyl linker. This molecular architecture makes it a valuable intermediate for the synthesis of photoaffinity labels and cross-linking agents used in advanced biochemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for applications in proteomics, drug discovery, and materials science where precise molecular targeting is required.

Application

• Photoaffinity Labeling: A critical reagent for creating covalent bonds with biological targets upon UV irradiation, enabling the study of protein-ligand interactions and binding sites.
• Bioconjugation & Cross-linking: Used to develop probes and linkers for attaching reporter molecules (e.g., fluorophores, biotin) to proteins, antibodies, or other biomolecules.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents, particularly in areas targeting specific enzymes or receptors.
• Proteomics Research: Employed in activity-based protein profiling (ABPP) and other advanced techniques to identify and characterize enzyme function within complex biological systems.
• Materials Science: Potential use in the development of photo-responsive polymers and smart materials where light-triggered cross-linking is desired.

Basic Information

Product Name	4(5)-(2-(4-Azido-2-Nitroanilino)Ethyl)Imidazole
CAS No.	83539-24-6
Molecular Formula	C11H12N8O2
Molecular Weight	288.27 g/mol
Synonyms	1-(2-(4-Azido-2-nitroanilino)ethyl)-1H-imidazole; 1-[2-[(4-Azido-2-nitrophenyl)amino]ethyl]imidazole; 4(5)-[2-(4-Azido-2-nitroanilino)ethyl]imidazole; N-(4-Azido-2-nitrophenyl)-N'-(2-imidazol-4-ylethyl)ethylenediamine (related form); Photoaffinity labeling agent 83539-24-6
EINECS	Contact for details

Quality Control

Our 4(5)-(2-(4-Azido-2-Nitroanilino)Ethyl)Imidazole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its strictly light-sensitive nature and the presence of an azide functional group, the container must be kept in opaque or amber glass and stored away from direct light exposure and heat sources. Handle and store in accordance with all applicable laboratory safety regulations.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.