Description

4-Pyridinecarbonitrile, 3-Amino-5-Methoxy-2-Methyl- is a high-purity, multi-functional heterocyclic building block of significant commercial importance. Its unique molecular structure, featuring both amino and cyano substituents on a methoxy-substituted pyridine ring, makes it a versatile intermediate for synthesizing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors seeking to create novel active ingredients. Its reliable quality and consistent supply are critical for accelerating drug discovery and fine chemical production pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Pyridinecarbonitrile, 3-Amino-5-Methoxy-2-Methyl-
CAS No.	83537-58-0
Molecular Formula	C8H9N3O
Molecular Weight	163.18 g/mol
Synonyms	3-Amino-5-methoxy-2-methylisonicotinonitrile; 3-Amino-5-methoxy-2-methylpyridine-4-carbonitrile; 2-Methyl-3-amino-5-methoxy-4-cyanopyridine; 4-Cyano-3-amino-5-methoxy-2-methylpyridine; 5-Methoxy-2-methyl-3-aminopyridine-4-carbonitrile; Isonicotinonitrile, 3-amino-5-methoxy-2-methyl-; 3-Amino-5-methoxy-2-methyl-4-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarbonitrile, 3-Amino-5-Methoxy-2-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.