Description

Ethyl 2-(Difluoromethylthio)Acetate is a specialized organofluorine and organosulfur building block of significant interest in advanced chemical synthesis. This compound matters for its unique molecular architecture, which combines a difluoromethylthio group with an ester functionality, enabling precise modifications to target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the difluoromethylthio moiety into drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the fluorine and sulfur atoms can contribute to improved activity and selectivity.
• Material Science Precursor: Serves as a building block for specialty polymers and advanced materials with tailored surface properties.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex sulfur- and fluorine-containing molecules for various applications.
• Ligand and Catalyst Development: Useful in the preparation of novel ligands or organocatalysts that leverage the electronic properties of the difluoromethylthio group.

Basic Information

Product Name	Ethyl 2-(Difluoromethylthio)Acetate
CAS No.	83494-29-5
Molecular Formula	C5H8F2O2S
Molecular Weight	170.18 g/mol
Synonyms	Ethyl (difluoromethylthio)acetate; Acetic acid, 2-[(difluoromethyl)thio]-, ethyl ester; 2-[(Difluoromethyl)thio]acetic acid ethyl ester; Ethyl 2-[(difluoromethyl)sulfanyl]acetate; Ethyl(difluoromethylthio)acetate; SCHEMBL2180621; 83494-29-5
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Difluoromethylthio)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.