Description

1-Pyrrolidinecarboxylicacid,3-Hydroxy-,Methylester(9Ci) is a specialized pyrrolidine derivative, a high-value intermediate in fine chemical synthesis. This compound matters for its role as a versatile chiral building block, enabling the construction of complex molecules with precise stereochemistry. It is primarily needed by research institutions and pharmaceutical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. The product is supplied under the CAS number 83487-19-8.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides requiring specific stereoisomers for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into the backbone of peptidomimetic compounds to modulate biological activity and stability.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways in organic chemistry.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers with tailored properties.

Basic Information

Product Name	1-Pyrrolidinecarboxylicacid,3-Hydroxy-,Methylester(9Ci)
CAS No.	83487-19-8
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	Methyl 3-hydroxypyrrolidine-1-carboxylate; 3-Hydroxy-1-pyrrolidinecarboxylic acid methyl ester; 1-Carbomethoxy-3-hydroxypyrrolidine; 3-Hydroxypyrrolidine-1-carboxylic acid methyl ester; (3R)-3-Hydroxypyrrolidine-1-carboxylic acid methyl ester (for enantiopure form); (3S)-3-Hydroxypyrrolidine-1-carboxylic acid methyl ester (for enantiopure form); 1-Pyrrolidinecarboxylic acid, 3-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxylicacid,3-Hydroxy-,Methylester(9Ci) is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis for stereochemical integrity, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grades)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.