Description

1-(((2-Chloroethyl)Nitrosoamino)Carbonyl)-L-Prolyl-L-Leucinamide is a specialized synthetic peptide derivative with a complex molecular architecture. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the study of enzyme inhibition and targeted therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules and proteomics research.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis of novel protease inhibitors and other therapeutic peptides.
• Biochemical Studies: Used as a tool compound in enzymology to investigate enzyme-substrate interactions and inhibition mechanisms.
• Proteomics & Chemical Biology: Employed in the design and development of activity-based probes for labeling and studying specific enzyme families.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and peptide science.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the custom synthesis of complex, high-value peptide derivatives for clients.
• Reference Standard: Provides a high-purity material for analytical method development, validation, and quality control in peptide manufacturing.

Basic Information

Product Name	1-(((2-Chloroethyl)Nitrosoamino)Carbonyl)-L-Prolyl-L-Leucinamide
CAS No.	83472-40-6
Molecular Formula	C₁₆H₂₈ClN₅O₄
Molecular Weight	389.88 g/mol
Synonyms	L-Prolyl-L-leucinamide, 1-[[(2-chloroethyl)nitrosoamino]carbonyl]-; N-[(2-Chloroethyl)nitrosoamino]carbonyl-L-prolyl-L-leucinamide; 1-[(N-Nitroso-N-(2-chloroethyl)carbamoyl)]-L-prolyl-L-leucinamide; NSC 338720; Chloroethylnitrosocarbamoyl-Pro-Leu-NH₂; CENU-Pro-Leu-NH₂ analog; Peptide chloronitrosourea derivative
EINECS	Contact for details

Quality Control

Our 1-(((2-Chloroethyl)Nitrosoamino)Carbonyl)-L-Prolyl-L-Leucinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications. Our commitment to quality assurance guarantees material integrity and reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.