Description

D-Alanine, n-Hydroxy-, 1,1-Dimethylethyl Ester (9Ci) is a specialized, high-purity amino acid derivative, identified by CAS NO 83451-16-5. This compound serves as a critical chiral building block and protecting group intermediate in advanced organic synthesis, enabling the precise construction of complex molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-fidelity intermediates for peptide mimetics, active pharmaceutical ingredients (APIs), and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs, enzyme inhibitors, and novel therapeutic candidates.
• Agrochemical Research: Used in developing chiral active ingredients for herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation & Probe Development: Utilized in creating labeled peptides and molecular probes for biochemical and diagnostic applications.
• Fine Chemical Synthesis: Acts as a versatile building block for synthesizing complex natural products and specialty chemicals.
• Academic & Industrial R&D: Employed in methodological development and exploratory chemistry within research laboratories.

Basic Information

Product Name	D-Alanine, n-Hydroxy-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	83451-16-5
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	tert-Butyl N-hydroxy-D-alaninate; D-Alanine, N-hydroxy-, 1,1-dimethylethyl ester; N-Hydroxy-D-alanine tert-butyl ester; (R)-2-((tert-Butoxycarbonyl)amino)propanoic acid N-oxide; Boc-D-alanine N-oxide tert-butyl ester; tert-Butyl (R)-2-(hydroxyamino)propanoate
EINECS	Contact for details

Quality Control

Our D-Alanine, n-Hydroxy-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.