Description

2-Oxo-4-Phenylbutyric Acid Methyl Ester is a versatile keto ester intermediate of significant importance in synthetic organic chemistry. Its value lies in its bifunctional structure, featuring both a reactive ketone and an ester group, which makes it a key building block for constructing complex molecular frameworks. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for the production of active pharmaceutical ingredients (APIs), chiral auxiliaries, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug molecules, particularly those containing phenylbutyric acid derivatives or γ-lactam structures.
• Chiral Synthesis: Serves as a starting material or intermediate for the preparation of enantiomerically pure compounds via asymmetric synthesis or resolution techniques.
• Fine Chemical Production: Used in the manufacture of agrochemicals, flavors, fragrances, and advanced material precursors.
• Research & Development: Employed in academic and industrial laboratories for method development and exploring new synthetic pathways.
• Peptidomimetic Chemistry: Acts as a scaffold for designing and synthesizing peptide analogs and protease inhibitors.

Basic Information

Product Name	2-Oxo-4-Phenylbutyric Acid Methyl Ester
CAS No.	83402-87-3
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	Methyl 2-Oxo-4-phenylbutyrate; Methyl 4-Phenyl-2-oxobutyrate; 4-Phenyl-2-oxobutanoic Acid Methyl Ester; 2-Keto-4-phenylbutyric Acid Methyl Ester; α-Keto-γ-phenylbutyric Acid Methyl Ester; Benzylacetone-2-carboxylic Acid Methyl Ester; Methyl (4-Phenyl-2-oxo)butyrate
EINECS	Contact for details

Quality Control

Our 2-Oxo-4-Phenylbutyric Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.