Description

n-Acetyl-Thiomuramyl-Alanyl-Isoglutamine is a synthetic muramyl dipeptide (MDP) derivative, a key structural motif recognized by the innate immune system. This compound is of significant interest for its role as a potent immunomodulator and adjuvant in vaccine research and development. It is primarily utilized by pharmaceutical R&D teams and biotech companies focused on novel immunotherapies, vaccine formulations, and immunological studies.

Application

• Immunological Research: As a reference standard and active component in studies of NOD2 receptor activation and innate immune signaling pathways.
• Vaccine Adjuvant Development: Investigated for enhancing the efficacy and longevity of immune responses in next-generation prophylactic and therapeutic vaccines.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of more complex immunostimulatory compounds and drug candidates.
• Cell Culture & In Vitro Studies: Used to stimulate immune cells in culture models to study cytokine production and cellular responses.

Basic Information

Product Name	n-Acetyl-Thiomuramyl-Alanyl-Isoglutamine
CAS No.	83375-11-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Acetylmuramyl-Alanyl-Isoglutamine; MDP Derivative; N-Acetylmuramyl-L-alanyl-D-isoglutamine analog; Thiomuramyl Dipeptide; Immunoadjuvant Peptide; NOD2 Ligand; 83375-11-5; L-Alanine, N-acetyl-6-O-[(2-acetamido-2-deoxy-3-O-[(R)-1-carboxyethyl]-β-D-glucopyranosyl]thio]-D-isoglutaminyl-
EINECS	Contact for details

Quality Control

Our n-Acetyl-Thiomuramyl-Alanyl-Isoglutamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.