Description

6-Methyl-n-(1H-Tetrazol-5-Yl)-2-Pyridinecarboxamide is a high-purity heterocyclic organic compound featuring a pyridine core linked to a tetrazole moiety. This specialized structure makes it a valuable pharmaceutical intermediate and research chemical for developing novel active ingredients. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams seeking to incorporate unique pharmacophores into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting cardiovascular or metabolic diseases.
• Angiotensin II Receptor Antagonist Research: Serves as a core scaffold or precursor in the development of sartan-class antihypertensive agents.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to explore new bioactive compounds with the tetrazole pharmacophore.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Biochemical Research: May be used as a ligand or inhibitor in enzymatic studies due to its ability to mimic carboxylate groups.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	6-Methyl-n-(1H-Tetrazol-5-Yl)-2-Pyridinecarboxamide
CAS No.	83282-08-0
Molecular Formula	C8H8N6O
Molecular Weight	204.19 g/mol
Synonyms	2-Pyridinecarboxamide, N-(1H-tetrazol-5-yl)-6-methyl-; 6-Methyl-2-pyridinecarboxylic acid (1H-tetrazol-5-yl)amide; 6-Methyl-N-(1H-tetrazol-5-yl)picolinamide; 6-Methyl-N-(2H-tetrazol-5-yl)pyridine-2-carboxamide; Losartan intermediate; Tetrazole picolinamide derivative; 83282-08-0; 5-(6-Methylpicolinamido)-1H-tetrazole
EINECS	Contact for details

Quality Control

Our 6-Methyl-n-(1H-Tetrazol-5-Yl)-2-Pyridinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.