Description

Ethyl 3,4-Dihydroxyphenylacetate is a high-purity catechol derivative ester, serving as a versatile and critical synthetic intermediate in advanced chemical manufacturing. Its core value lies in providing a protected catechol moiety, enabling precise synthesis of complex molecules where controlled oxidation or specific functional group manipulation is required. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors developing active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of catechol-based active pharmaceutical ingredients (APIs), including potential candidates for neurodegenerative and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require a stable dihydroxyphenyl backbone.
• Fine Chemical & Flavor/Fragrance Precursor: Serves as a starting material for synthesizing complex aroma chemicals and specialty esters used in high-value applications.
• Antioxidant & Polymer Additive Research: Investigated as a monomer or stabilizer precursor for developing polymers with enhanced UV resistance and oxidative stability.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies related to catechol-O-methyltransferase (COMT) and other oxidoreductases.
• Material Science: Acts as a ligand or functionalizing agent in the development of metal-organic frameworks (MOFs) and catalytic systems.

Basic Information

Product Name	Ethyl 3,4-Dihydroxyphenylacetate
CAS No.	83112-21-4
Molecular Formula	C10H12O4
Molecular Weight	196.20 g/mol
Synonyms	Ethyl (3,4-Dihydroxyphenyl)acetate; 3,4-Dihydroxyphenylacetic Acid Ethyl Ester; Ethyl Homoprotocatechuate; Ethyl 2-(3,4-Dihydroxyphenyl)acetate; Homoprotocatechuic Acid Ethyl Ester; 2-(3,4-Dihydroxyphenyl)acetic Acid Ethyl Ester; Ethyl 4,5-Dihydroxyphenylacetate
EINECS	Contact for details

Quality Control

Our Ethyl 3,4-Dihydroxyphenylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.