Description

2,3-o-Isopropylidene-L-Ribonic Acid-1,4-Lactone (Wx640385) is a high-purity chiral lactone derivative, serving as a critical protected intermediate in organic synthesis. Its value lies in providing a versatile and enantiomerically pure scaffold for constructing complex nucleoside analogs and other bioactive molecules. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those developing antiviral agents, enzyme inhibitors, and novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Fine Chemical Synthesis: Used in the preparation of complex carbohydrates, glycomimetics, and other specialty organic compounds.
• Biochemical Research: Serves as a precursor for labeled compounds or probes used in metabolic pathway studies and enzymology.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to introduce chirality.
• Academic & R&D: Fundamental reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Item	Details
Product Name	2,3-o-Isopropylidene-L-Ribonic Acid-1,4-Lactone (Wx640385)
CAS No.	83085-15-8
Molecular Formula	C8H12O5
Molecular Weight	188.18 g/mol
Synonyms	L-Ribonic acid, 2,3-O-(1-methylethylidene)-, 1,4-lactone; (3aR,6S,6aR)-6-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4(3aH)-one; 2,3-O-Isopropylidene-L-ribono-1,4-lactone; L-Ribono-1,4-lactone, 2,3-O-isopropylidene-; Isopropylidene-L-ribonolactone
EINECS	Contact for details

Quality Control

Every batch of 2,3-o-Isopropylidene-L-Ribonic Acid-1,4-Lactone is manufactured under a strict quality management system. We perform comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure the product meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.