Description

6-Oxabicyclo(3.1.0)Hex-3-Ene-2-Methanol, 2-Hydroxy-4-Isocyano-α-Me Thyl-, (1-Alpha,2-Beta,2(R*),5-Alpha)-(-)- is a complex, stereochemically defined bicyclic oxirane derivative that serves as a versatile chiral building block in advanced organic synthesis. Its unique fused-ring structure, incorporating both an oxirane and an isocyano group, makes it a high-value intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require sophisticated scaffolds for drug discovery and the synthesis of bioactive molecules.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key precursor for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring complex, multi-cyclic frameworks.
• Ligand and Catalyst Development: Used in the preparation of specialized chiral ligands and organocatalysts for asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents with specific stereochemical requirements for enhanced efficacy.
• Material Science Precursor: Potential building block for specialty polymers and advanced materials where its rigid bicyclic structure can impart specific physical properties.
• Academic and R&D Laboratories: Serves as a valuable tool for methodological studies in organic chemistry, including cycloaddition reactions and stereoselective transformations.

Basic Information

Product Name	6-Oxabicyclo(3.1.0)Hex-3-Ene-2-Methanol, 2-Hydroxy-4-Isocyano-α-Me Thyl-, (1-Alpha,2-Beta,2(R*),5-Alpha)-(-)-
CAS No.	83058-95-1
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	(-)-2-Hydroxy-4-isocyano-α-methyl-6-oxabicyclo[3.1.0]hex-3-ene-2-methanol; (1R,2S,5S)-2-Hydroxy-4-isocyano-2-methyl-6-oxabicyclo[3.1.0]hex-3-ene-2-methanol; Bicyclic Oxirane Isonitrile; Chiral Oxabicyclohexene Isocyanide; Advanced Chiral Synthon
EINECS	Contact for details

Quality Control

This high-purity synthetic intermediate is produced under strict quality control protocols. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality management system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.