Description

(2R)-5-Bromo-3-(2-Pyrrolidinyl)Pyridine is a high-purity chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for the development of novel, stereoselective pharmaceuticals and bioactive molecules. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Ligand Precursor: Used in the synthesis of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing novel, optically active pesticides and herbicides with improved efficacy and environmental profiles.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study biological pathways and protein interactions.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry and medicinal chemistry projects.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.

Basic Information

Product Name	(2R)-5-Bromo-3-(2-Pyrrolidinyl)Pyridine
CAS No.	83023-56-7
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	(R)-5-Bromo-3-(pyrrolidin-2-yl)pyridine; (2R)-5-Bromo-3-(2-pyrrolidinyl)pyridine; 5-Bromo-3-[(2R)-2-pyrrolidinyl]pyridine; (R)-5-Bromo-3-(2-pyrrolidinyl)pyridine; 83023-56-7; (R)-5-Bromo-3-pyrrolidin-2-ylpyridine; 3-(2R-Pyrrolidin-2-yl)-5-bromopyridine
EINECS	Contact for details

Quality Control

Our (2R)-5-Bromo-3-(2-Pyrrolidinyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.