Description

(+)-2-Ethenyl-5-Hydroxy-5-Isocyano-2-Cyclopenten-1-One CAS NO 83016-50-6 is a specialized chiral cyclopentenone derivative featuring both hydroxyl and isocyano functional groups. This unique molecular architecture makes it a valuable advanced synthetic intermediate and building block for constructing complex organic molecules. It is primarily utilized by pharmaceutical research and fine chemical synthesis laboratories engaged in the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates and bioactive molecules.
• Asymmetric Synthesis: Utilized as a building block for constructing complex, enantiomerically pure natural product analogs and specialty chemicals.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value agrochemicals, flavors, and fragrances.
• Academic & R&D: Used in university and institutional research for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	(+)-2-Ethenyl-5-Hydroxy-5-Isocyano-2-Cyclopenten-1-One
CAS No.	83016-50-6
Molecular Formula	C8H7NO2
Molecular Weight	149.15 g/mol
Synonyms	(+)-5-Isocyano-5-hydroxy-2-vinyl-2-cyclopenten-1-one; (5R)-5-Hydroxy-5-isocyano-2-ethenyl-2-cyclopenten-1-one; 5-Isocyano-5-hydroxy-2-vinyl-2-cyclopenten-1-one; 2-Cyclopenten-1-one, 5-isocyano-5-hydroxy-2-ethenyl-, (5R)-; Chiral Isocyanocyclopentenone; 2-Vinyl-5-hydroxy-5-isocyano-2-cyclopenten-1-one
EINECS	Contact for details

Quality Control

Our (+)-2-Ethenyl-5-Hydroxy-5-Isocyano-2-Cyclopenten-1-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure consistent high quality and enantiomeric excess. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere if possible to maximize stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.