Description

2-(Bromomethyl)-6-Nitropyridine is a versatile and high-value brominated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a reactive bromomethyl group and an electron-withdrawing nitro substituent, makes it indispensable for constructing complex heterocyclic systems and functionalized molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as API synthesis and the development of novel ligands.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating sophisticated nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or photoactive compounds, due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The bromomethyl group acts as an excellent electrophile for nucleophilic substitution (SN2) reactions, while the nitro group can be further reduced or transformed, enabling diverse molecular diversification.

Basic Information

Product Name	2-(Bromomethyl)-6-Nitropyridine
CAS No.	83004-08-4
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	6-Nitro-2-(bromomethyl)pyridine; 2-Bromomethyl-6-nitropyridine; (6-Nitro-2-pyridinyl)methyl bromide; 6-Nitro-2-pyridinemethyl bromide; 2-Pyridinemethanol, 6-nitro-, bromide; Bromo(6-nitro-2-pyridyl)methane
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-6-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.